Efficacy of topical 5% fluorouracil (5%- FU) needling in vitiligo

فعالية الحقن الموضعي بالإبر الدقيقة لـ fluorouracil  5% في علاج البهاق

المؤلفون

  • Mai Abdulkhaliq Ibrahiem, Mohammed Adel Ismaiel

الكلمات المفتاحية:

vitiligo
البهاق
5- fluorouracil
5-فلورويوراسيل
micro needling
الابر الدقيقة
repigmentation
عودة التصبغ

الملخص

Objective: The aim of this study is to assess the efficacy of topical 5- fluorouracil (5%- FU) with micro needling in treating stable vitiligo. In addition to, assessment the side effects of the treatment.

Patients and Methods: A Prospective study (Before& After) conducted for the period one year (April 2019- April2020)at Tishreen University Hospital in Lattakia- Syria, 31 patients with stable vitiligo who received treatment with micro needling and topical 5- fluorouracil (5%- FU) were included in this study.

Results : The median age was 36 years, 67.70% of patients were female. Focal type was found in 61.3%, and most common sites of vitiligo involvement were hand and feet (33.7%), followed by trunk (24.8%)and extremities (24.8%). After 6 months of treatment, improvement was excellent in 63.4%, and very good in 23.8%. The lesions of neck and trunk were responded better to treatment than those in other parts of the body. Regarding of side effects, pain, erythema, and itching were reported in 100% followed by ulceration in (16.1%).

Conclusion: Topical 5%- fluorouracil (5%- FU) with needling appears to be an effective and safe method in treating stable vitiligo. Except of pain, erythema, and itching after procedure, significant complications not occurred in most patients.

السيرة الشخصية للمؤلف

Mai Abdulkhaliq Ibrahiem, Mohammed Adel Ismaiel

 

Medicine College || Tishreen University || Syria

التنزيلات

منشور

2021-12-27

كيفية الاقتباس

1.
Efficacy of topical 5% fluorouracil (5%- FU) needling in vitiligo: فعالية الحقن الموضعي بالإبر الدقيقة لـ fluorouracil  5% في علاج البهاق. JMPS [انترنت]. 27 ديسمبر، 2021 [وثق 28 مارس، 2024];5(4):34-28. موجود في: https://journals.ajsrp.com/index.php/jmps/article/view/4422

إصدار

القسم

المقالات

كيفية الاقتباس

1.
Efficacy of topical 5% fluorouracil (5%- FU) needling in vitiligo: فعالية الحقن الموضعي بالإبر الدقيقة لـ fluorouracil  5% في علاج البهاق. JMPS [انترنت]. 27 ديسمبر، 2021 [وثق 28 مارس، 2024];5(4):34-28. موجود في: https://journals.ajsrp.com/index.php/jmps/article/view/4422